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All Peptides

Evidence-graded profiles for every peptide we cover. Each entry links to a detailed breakdown of mechanism, dosing, FDA status, and clinical evidence — no vendors, no affiliates.

43 peptides covered9 FDA-approved21 therapeutic categories

5-Amino-1MQ

C+

5-Amino-1-Methylquinolinium

A small-molecule NNMT inhibitor that has produced fat loss and improved muscle stem-cell function in obese rodents. No human RCTs yet.

Fat LossLongevity
Not FDA-approved

Afamelanotide

A

Afamelanotide (Scenesse)

An FDA-approved selective MC1R agonist used to increase eumelanin density in erythropoietic protoporphyria patients. Off-label cosmetic tanning use is widespread internationally.

Skin & Hair
✓ FDA-approved

AOD-9604

C+

Anti-Obesity Drug 9604

A modified fragment of human growth hormone (hGH 176-191) that stimulates fat breakdown without the growth-promoting or diabetogenic effects of full HGH.

Weight LossFat Loss
Not FDA-approved

ARA-290

B

ARA-290 (Cibinetide)

An 11-amino-acid peptide derived from the helix-B region of erythropoietin. Activates the tissue-protective receptor without erythropoietic side effects. Investigated for neuropathy and inflammation.

Anti-InflammatoryNeuroprotection
Not FDA-approved

BPC-157

B+

Body Protection Compound-157

A 15-amino-acid peptide derived from gastric juice. The most popular recovery peptide with 100+ preclinical studies showing accelerated healing of tendons, ligaments, muscle, gut lining, and nerves.

Recovery & HealingGut Health
Not FDA-approved

Cagrilintide

A

Cagrilintide (long-acting amylin analog)

A once-weekly amylin analog that reduces appetite via the area postrema. Combined with semaglutide ('CagriSema') it has produced ~22% weight loss in trial data.

Weight LossMetabolic Health
Not FDA-approved

Cerebrolysin

B

Cerebrolysin (porcine brain peptide complex)

A standardized mixture of low-molecular-weight peptides from porcine brain. Decades of stroke, dementia, and TBI trial data — modest but consistent cognitive recovery effects.

Cognitive EnhancementNeuroprotection
Not FDA-approved in US

CJC-1295 (no DAC)

B

Modified Growth Hormone Releasing Factor 1-29

A growth hormone releasing hormone (GHRH) analog most commonly stacked with Ipamorelin to stimulate natural GH pulsatile release without disrupting the hypothalamic axis.

Growth HormoneAnti-Aging & LongevityRecovery & Healing
Not FDA-approved

Dihexa

C

Dihexa (PNB-0408)

An angiotensin IV-derived hexapeptide that mimics hepatocyte growth factor (HGF)/c-Met signaling and produced rapid synaptogenesis in animal models. No human trials.

Cognitive EnhancementNeuroprotection
Not FDA-approved

DSIP

C

Delta Sleep-Inducing Peptide

A nonapeptide originally isolated from rabbit blood after EEG-defined slow-wave sleep induction. Inconsistent human evidence for sleep but explored for stress and analgesia.

SleepNeuroprotection
Not FDA-approved

Epitalon

C+

Epitalon (Epithalon, AEDG)

A synthetic tetrapeptide that reportedly upregulates telomerase activity. Russian longevity studies suggest mortality reductions but Western RCTs are absent.

Anti-Aging & LongevityLongevity
Not FDA-approved

GHK-Cu

B+

Copper Peptide GHK-Cu

A naturally occurring copper-binding tripeptide that modulates 4,000+ human genes. The most studied peptide for skin rejuvenation with both preclinical and clinical topical evidence.

Anti-Aging & LongevitySkin & HairHair
Not FDA-approved

GHRH (1–44)

A

Growth Hormone Releasing Hormone, full sequence

The full 44-amino-acid GHRH sequence. The natural pituitary stimulus for GH release. Largely supplanted in clinical use by sermorelin/tesamorelin but remains a research and diagnostic tool.

Growth Hormone
✓ FDA-approved

GHRP-2

B

Growth Hormone Releasing Peptide 2

A potent synthetic ghrelin-mimetic GH secretagogue. Drives strong GH spikes but raises cortisol and prolactin more than newer alternatives like Ipamorelin.

Growth HormoneAnti-Aging & Longevity
Not FDA-approved

GHRP-6

B

Growth Hormone Releasing Peptide 6

An older GHS that produces strong appetite stimulation in addition to GH release. Largely supplanted by Ipamorelin and GHRP-2 for clinical use but still common in research stacks.

Growth HormoneAppetite
Not FDA-approved

Glutathione (GSH)

B

Reduced L-Glutathione

Technically a tripeptide (γ-glutamyl-cysteinyl-glycine) and the body's primary antioxidant. Often grouped with peptide therapy in IV/compounded form for liver support and oxidative stress.

AntioxidantLongevity
Not FDA-approved as therapeutic

Gonadorelin

A

Gonadorelin (GnRH)

Synthetic GnRH used clinically to stimulate LH/FSH release. In testosterone replacement therapy, used pulsatile to preserve testicular size and fertility instead of hCG.

Sexual HealthFertility & HPG Axis
✓ FDA-approved

Hexarelin

B

Hexarelin (HEX)

The strongest GH-releasing hexapeptide and one of the few peptides with documented direct cardiac benefits in animal models. Tachyphylaxis (diminished response over time) limits long-term use.

Growth HormoneRecovery & Healing
Not FDA-approved

Humanin

B

Humanin (HN)

A 24-amino-acid mitochondrial-derived peptide with cytoprotective effects across Alzheimer's, diabetes, and atherosclerosis preclinical models. Endogenous levels decline sharply with age.

Mitochondrial FunctionLongevityNeuroprotection
Not FDA-approved

Ipamorelin

B

Ipamorelin Acetate

A selective growth hormone secretagogue that triggers GH release from the pituitary without significantly raising cortisol or prolactin. The safest GH peptide with the fewest side effects.

Growth HormoneAnti-Aging & Longevity
Not FDA-approved

Kisspeptin-10

B

Kisspeptin-10 (KP-10)

A 10-amino-acid neuropeptide that triggers GnRH release. Studied as a more physiologic alternative to hCG/GnRH for fertility, libido, and HPG-axis assessment.

Sexual HealthFertility & HPG Axis
Not FDA-approved

KPV

C+

α-MSH Tripeptide KPV

The C-terminal tripeptide of α-MSH with documented anti-inflammatory activity in IBD and dermatitis preclinical models. Frequently delivered orally and topically.

Anti-InflammatoryGut HealthSkin & Hair
Not FDA-approved

Larazotide

B+

Larazotide Acetate (AT-1001)

An 8-amino-acid oral peptide that tightens intestinal tight junctions by antagonizing zonulin signaling. The most-studied 'leaky gut' peptide with celiac trial data.

Gut Health
Not FDA-approved

Liraglutide

A+

Liraglutide (Saxenda / Victoza)

The original once-daily GLP-1 receptor agonist. Lower weight-loss magnitude than semaglutide but a longer real-world track record across diabetes and obesity.

Weight LossMetabolic Health
✓ FDA-approved

LL-37

B

Cathelicidin LL-37

The only human cathelicidin antimicrobial peptide. Active against bacteria, viruses, and biofilms. Investigated topically for infected wounds and mucosal infections.

Immune ModulationAnti-Inflammatory
Not FDA-approved

Melanotan II

C+

Melanotan II (MT-II)

A non-selective melanocortin agonist (MC1R/MC3R/MC4R) that produces tanning and erection effects. Significant safety concerns including melanoma case reports.

Skin & HairSexual Health
Not FDA-approved

MK-677

B+

Ibutamoren (MK-677)

An orally active ghrelin-receptor agonist that drives 24-hour increases in GH and IGF-1. Technically a non-peptide small molecule but always grouped with GH peptides.

Growth HormoneAnti-Aging & Longevity
Not FDA-approved

MOTS-c

B

Mitochondrial-derived peptide MOTS-c

A 16-amino-acid mitochondrial-derived peptide that improves insulin sensitivity and exercise capacity in animal models. Among the most promising 'mitokines' for metabolic aging.

Metabolic HealthLongevity
Not FDA-approved

PDA

C+

Pentadeca Arginate (PDA)

A 15-amino-acid arginate analog developed as a more stable, sometimes more bioavailable alternative to BPC-157. Limited published research; popular among compounding pharmacies in 2025–2026.

Recovery & HealingAnti-Inflammatory
Not FDA-approved

Pinealon

C

Pinealon (EDR)

A short tripeptide developed in Russia for cognitive aging and oxidative stress. Limited Western clinical evidence.

Cognitive EnhancementLongevity
Not FDA-approved

PT-141

A

Bremelanotide (Vyleesi)

A melanocortin receptor agonist that works directly on the nervous system to increase sexual desire. The only FDA-approved peptide for sexual dysfunction that acts on the brain rather than vascular system.

Sexual Health
✓ FDA-approved

Retatrutide

A

Retatrutide (LY3437943)

Triple agonist at GLP-1, GIP, and glucagon receptors. Phase 2 produced 24.2% mean weight reduction at 48 weeks — the highest ever in a clinical obesity trial.

Weight LossMetabolic Health
Not FDA-approved

Selank

B

Selank (TP-7)

A synthetic analog of tuftsin with anxiolytic and nootropic properties. Modulates GABA and serotonin systems to reduce anxiety without sedation.

Cognitive EnhancementAnxiety & Stress
Not FDA-approved in US

Semaglutide

A+

Semaglutide (Ozempic / Wegovy)

A GLP-1 receptor agonist and the gold standard for evidence-based weight loss peptide therapy. Demonstrated 14.9–16.9% mean body weight reduction in the landmark STEP trials.

Weight LossMetabolic Health
✓ FDA-approved

Semax

B

Semax (MEHFPGP)

A synthetic ACTH fragment that increases BDNF levels and enhances focus, memory, and mental clarity. Delivered intranasally for rapid cognitive effects.

Cognitive EnhancementNeuroprotection
Not FDA-approved in US

Sermorelin

B+

Sermorelin Acetate (GHRH 1-29)

The original synthetic GHRH(1–29) and the most accessible GH-stimulating peptide for age-related hormone decline. Stimulates the body's own pulsatile GH release rather than replacing it.

Growth HormoneAnti-Aging & Longevity
✓ FDA-approved

SS-31

B+

Elamipretide (SS-31)

A cell-permeable tetrapeptide that targets cardiolipin in the inner mitochondrial membrane. Investigated for primary mitochondrial myopathy, heart failure, and dry age-related macular degeneration.

Mitochondrial FunctionLongevity
Not FDA-approved

Survodutide

A

Survodutide (BI 456906)

A dual GLP-1 / glucagon receptor agonist with strong Phase 2 weight-loss and MASH data. Resolution of MASH in 83% of participants at the highest dose at week 48.

Weight LossMetabolic Health
Not FDA-approved

TB-500

B

Thymosin Beta-4 Fragment

A synthetic fragment of thymosin beta-4 that promotes cell migration, blood vessel formation, and tissue repair. Often stacked with BPC-157 as the 'Wolverine Stack.'

Recovery & HealingAnti-Inflammatory
Not FDA-approved

Tesamorelin

A

Tesamorelin (Egrifta)

An FDA-approved GHRH analog that stimulates natural growth hormone production. Clinically proven to reduce visceral adipose tissue and increasingly used off-label for body recomposition.

Growth HormoneFat Loss
✓ FDA-approved

Thymosin Alpha-1

A

Thymosin Alpha-1 (Tα1)

A 28-amino-acid thymic peptide that matures and modulates T-cells. Used internationally as an adjunct in hepatitis, sepsis, and immune-compromised cancer care.

Immune ModulationAnti-Inflammatory
Approved in 35+ countries for hepatitis B/C, immune support; not FDA-approved in US (orphan-drug designations)

Tirzepatide

A+

Tirzepatide (Mounjaro / Zepbound)

A dual GIP/GLP-1 receptor agonist that achieved up to 22.5% mean weight loss in the SURMOUNT-1 trial — the highest of any FDA-approved weight loss medication.

Weight LossMetabolic Health
✓ FDA-approved

VIP

B

Vasoactive Intestinal Peptide

A 28-amino-acid neuropeptide with broad immunomodulatory effects. Used clinically (intranasal) by some practitioners for chronic inflammatory response syndrome (CIRS).

Anti-InflammatoryNeuroprotection
Not FDA-approved