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Evidence: BCognitive Enhancementneuroprotection

Semax

Semax (MEHFPGP)

A synthetic ACTH fragment that increases BDNF levels and enhances focus, memory, and mental clarity. Delivered intranasally for rapid cognitive effects.

FDA Status

Not FDA-approved in US — approved in Russia for stroke and cognitive disorders

Typical Dose

200–600 mcg intranasal, morning

Evidence Grade

BLimited clinical + robust preclinical evidence

Clinics Indexed

89 providers have offered Semax in our tracked directory.

Key Reported Benefits

  • BDNF increase
  • Enhanced focus
  • Memory improvement
  • Neuroprotection

Benefits listed reflect commonly reported effects from clinical trials and practitioner use. Individual response varies. Evidence-grade B indicates limited clinical + robust preclinical evidence.

Regulatory & Safety Context

FDA status: Not FDA-approved in US — approved in Russia for stroke and cognitive disorders

This page is for educational purposes only and does not constitute medical advice. Peptide use outside of an FDA-approved indication should be discussed with a licensed medical professional. Source quality, cold-chain storage, and injection hygiene all materially affect safety outcomes.

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