Selank vs Semax
Both Selank and Semax are used for cognitive. Here's how their evidence, dosing, and regulatory status actually compare.
Selank
Evidence BSelank (TP-7)
A synthetic analog of tuftsin with anxiolytic and nootropic properties. Modulates GABA and serotonin systems to reduce anxiety without sedation.
View full Selank profile →Semax
Evidence BSemax (MEHFPGP)
A synthetic ACTH fragment that increases BDNF levels and enhances focus, memory, and mental clarity. Delivered intranasally for rapid cognitive effects.
View full Semax profile →Side-by-Side
| Attribute | Selank | Semax |
|---|---|---|
| Evidence Grade | B | B |
| FDA Status | Not FDA-approved in US — approved in Russia as anxiolytic | Not FDA-approved in US — approved in Russia for stroke and cognitive disorders |
| Typical Dose | 200–400 mcg intranasal, evening | 200–600 mcg intranasal, morning |
| Clinics Indexed | 72 | 89 |
| Categories | cognitive, anxiety | cognitive, neuroprotection |
Key reported benefits — Selank
- ✓Anxiety reduction
- ✓Stress resilience
- ✓Cognitive clarity
- ✓Immune modulation
Key reported benefits — Semax
- ✓BDNF increase
- ✓Enhanced focus
- ✓Memory improvement
- ✓Neuroprotection
Educational use only
This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.