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TB-500 vs Hexarelin

Both TB-500 and Hexarelin are used for recovery. Here's how their evidence, dosing, and regulatory status actually compare.

TB-500

Evidence B

Thymosin Beta-4 Fragment

A synthetic fragment of thymosin beta-4 that promotes cell migration, blood vessel formation, and tissue repair. Often stacked with BPC-157 as the 'Wolverine Stack.'

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Hexarelin

Evidence B

Hexarelin (HEX)

The strongest GH-releasing hexapeptide and one of the few peptides with documented direct cardiac benefits in animal models. Tachyphylaxis (diminished response over time) limits long-term use.

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Side-by-Side

AttributeTB-500Hexarelin
Evidence GradeBB
FDA StatusNot FDA-approved — Category 2 (reclassification to Cat 1 expected 2026)Not FDA-approved — research compound (cardioprotective signals investigated)
Typical Dose2 mg twice weekly (subcutaneous)100 mcg, 1–2 times daily (subcutaneous)
Clinics Indexed18341
Categoriesrecovery, anti-inflammatorygrowth-hormone, recovery

Key reported benefits — TB-500

  • Wound healing
  • Anti-inflammation
  • Tissue regeneration
  • Flexibility

Key reported benefits — Hexarelin

  • Strongest GH spike of GHRPs
  • Cardioprotective signals
  • Recovery

Educational use only

This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.

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