Hexarelin vs TB-500
Both Hexarelin and TB-500 are used for recovery. Here's how their evidence, dosing, and regulatory status actually compare.
Hexarelin
Evidence BHexarelin (HEX)
The strongest GH-releasing hexapeptide and one of the few peptides with documented direct cardiac benefits in animal models. Tachyphylaxis (diminished response over time) limits long-term use.
View full Hexarelin profile →TB-500
Evidence BThymosin Beta-4 Fragment
A synthetic fragment of thymosin beta-4 that promotes cell migration, blood vessel formation, and tissue repair. Often stacked with BPC-157 as the 'Wolverine Stack.'
View full TB-500 profile →Side-by-Side
| Attribute | Hexarelin | TB-500 |
|---|---|---|
| Evidence Grade | B | B |
| FDA Status | Not FDA-approved — research compound (cardioprotective signals investigated) | Not FDA-approved — Category 2 (reclassification to Cat 1 expected 2026) |
| Typical Dose | 100 mcg, 1–2 times daily (subcutaneous) | 2 mg twice weekly (subcutaneous) |
| Clinics Indexed | 41 | 183 |
| Categories | growth-hormone, recovery | recovery, anti-inflammatory |
Key reported benefits — Hexarelin
- ✓Strongest GH spike of GHRPs
- ✓Cardioprotective signals
- ✓Recovery
Key reported benefits — TB-500
- ✓Wound healing
- ✓Anti-inflammation
- ✓Tissue regeneration
- ✓Flexibility
Educational use only
This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.