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GHRP-6 vs GHRH (1–44)

Both GHRP-6 and GHRH (1–44) are used for growth-hormone. Here's how their evidence, dosing, and regulatory status actually compare.

GHRP-6

Evidence B

Growth Hormone Releasing Peptide 6

An older GHS that produces strong appetite stimulation in addition to GH release. Largely supplanted by Ipamorelin and GHRP-2 for clinical use but still common in research stacks.

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GHRH (1–44)

Evidence A

Growth Hormone Releasing Hormone, full sequence

The full 44-amino-acid GHRH sequence. The natural pituitary stimulus for GH release. Largely supplanted in clinical use by sermorelin/tesamorelin but remains a research and diagnostic tool.

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Side-by-Side

AttributeGHRP-6GHRH (1–44)
Evidence GradeBA
FDA StatusNot FDA-approved — research compoundFDA-approved (Geref) historically as diagnostic GH stimulant; current US availability limited
Typical Dose100–300 mcg, 1–3 times daily (subcutaneous)1 mcg/kg IV (diagnostic test)
Clinics Indexed6422
Categoriesgrowth-hormone, appetitegrowth-hormone

Key reported benefits — GHRP-6

  • GH release
  • Appetite stimulation
  • Cytoprotection

Key reported benefits — GHRH (1–44)

  • Endogenous GH stimulation
  • Diagnostic GH testing

Educational use only

This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.

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