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GHRP-2 vs GHRH (1–44)

Both GHRP-2 and GHRH (1–44) are used for growth-hormone. Here's how their evidence, dosing, and regulatory status actually compare.

GHRP-2

Evidence B

Growth Hormone Releasing Peptide 2

A potent synthetic ghrelin-mimetic GH secretagogue. Drives strong GH spikes but raises cortisol and prolactin more than newer alternatives like Ipamorelin.

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GHRH (1–44)

Evidence A

Growth Hormone Releasing Hormone, full sequence

The full 44-amino-acid GHRH sequence. The natural pituitary stimulus for GH release. Largely supplanted in clinical use by sermorelin/tesamorelin but remains a research and diagnostic tool.

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Side-by-Side

AttributeGHRP-2GHRH (1–44)
Evidence GradeBA
FDA StatusNot FDA-approved — research compound; previously studied as growth hormone deficiency diagnosticFDA-approved (Geref) historically as diagnostic GH stimulant; current US availability limited
Typical Dose100–300 mcg, 1–3 times daily (subcutaneous)1 mcg/kg IV (diagnostic test)
Clinics Indexed8622
Categoriesgrowth-hormone, anti-aginggrowth-hormone

Key reported benefits — GHRP-2

  • Strong GH release
  • Appetite stimulation
  • Muscle recovery

Key reported benefits — GHRH (1–44)

  • Endogenous GH stimulation
  • Diagnostic GH testing

Educational use only

This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.

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