GHK-Cu vs GHRP-2
Both GHK-Cu and GHRP-2 are used for anti-aging. Here's how their evidence, dosing, and regulatory status actually compare.
GHK-Cu
Evidence B+Copper Peptide GHK-Cu
A naturally occurring copper-binding tripeptide that modulates 4,000+ human genes. The most studied peptide for skin rejuvenation with both preclinical and clinical topical evidence.
View full GHK-Cu profile →GHRP-2
Evidence BGrowth Hormone Releasing Peptide 2
A potent synthetic ghrelin-mimetic GH secretagogue. Drives strong GH spikes but raises cortisol and prolactin more than newer alternatives like Ipamorelin.
View full GHRP-2 profile →Side-by-Side
| Attribute | GHK-Cu | GHRP-2 |
|---|---|---|
| Evidence Grade | B+ | B |
| FDA Status | Not FDA-approved — available as cosmetic ingredient and research compound | Not FDA-approved — research compound; previously studied as growth hormone deficiency diagnostic |
| Typical Dose | 1–2 mg daily SC or topical (5 days on / 2 off) | 100–300 mcg, 1–3 times daily (subcutaneous) |
| Clinics Indexed | 145 | 86 |
| Categories | anti-aging, skin, hair | growth-hormone, anti-aging |
Key reported benefits — GHK-Cu
- ✓Collagen synthesis
- ✓Wrinkle reduction
- ✓Hair growth
- ✓Wound healing
Key reported benefits — GHRP-2
- ✓Strong GH release
- ✓Appetite stimulation
- ✓Muscle recovery
Educational use only
This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.