What is the difference between Epitalon and Pinealon?

Epitalon (Epitalon (Epithalon, AEDG)) is graded C+ and is Not FDA-approved — Russian-origin research peptide. Pinealon (Pinealon (EDR)) is graded C and is Not FDA-approved — Russian-origin research peptide. They are commonly compared because they share the categories: longevity.

Which has stronger clinical evidence — Epitalon or Pinealon?

On our internal evidence scale, Epitalon is C+ and Pinealon is C. A+ indicates large RCTs plus FDA approval; C indicates primarily preclinical or anecdotal evidence.

What is the typical dose of Epitalon vs Pinealon?

Epitalon: 5–10 mg daily for 10–20 days, cycled (subcutaneous). Pinealon: 5–10 mg daily for 10–20 days (subcutaneous, cycled). Always work with a licensed clinician — peptide dosing should be individualized.

Epitalon vs Pinealon

Both Epitalon and Pinealon are used for longevity. Here's how their evidence, dosing, and regulatory status actually compare.

Epitalon

Evidence C+

Epitalon (Epithalon, AEDG)

A synthetic tetrapeptide that reportedly upregulates telomerase activity. Russian longevity studies suggest mortality reductions but Western RCTs are absent.

View full Epitalon profile →

Pinealon

Evidence C

Pinealon (EDR)

A short tripeptide developed in Russia for cognitive aging and oxidative stress. Limited Western clinical evidence.

View full Pinealon profile →

Side-by-Side

Attribute	Epitalon	Pinealon
Evidence Grade	C+	C
FDA Status	Not FDA-approved — Russian-origin research peptide	Not FDA-approved — Russian-origin research peptide
Typical Dose	5–10 mg daily for 10–20 days, cycled (subcutaneous)	5–10 mg daily for 10–20 days (subcutaneous, cycled)
Clinics Indexed	47	9
Categories	anti-aging, longevity	cognitive, longevity

Key reported benefits — Epitalon

✓Telomerase upregulation (preclinical)
✓Sleep/circadian normalization
✓Anti-aging signals

Key reported benefits — Pinealon

✓Cognitive function (preclinical)
✓Reduced oxidative damage
✓Sleep/circadian effects

Educational use only

This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.

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