Epitalon vs Ipamorelin
Both Epitalon and Ipamorelin are used for anti-aging. Here's how their evidence, dosing, and regulatory status actually compare.
Epitalon
Evidence C+Epitalon (Epithalon, AEDG)
A synthetic tetrapeptide that reportedly upregulates telomerase activity. Russian longevity studies suggest mortality reductions but Western RCTs are absent.
View full Epitalon profile →Ipamorelin
Evidence BIpamorelin Acetate
A selective growth hormone secretagogue that triggers GH release from the pituitary without significantly raising cortisol or prolactin. The safest GH peptide with the fewest side effects.
View full Ipamorelin profile →Side-by-Side
| Attribute | Epitalon | Ipamorelin |
|---|---|---|
| Evidence Grade | C+ | B |
| FDA Status | Not FDA-approved — Russian-origin research peptide | Not FDA-approved — Category 1 (compounding allowed) |
| Typical Dose | 5–10 mg daily for 10–20 days, cycled (subcutaneous) | 100–300 mcg before bed (subcutaneous) |
| Clinics Indexed | 47 | 195 |
| Categories | anti-aging, longevity | growth-hormone, anti-aging |
Key reported benefits — Epitalon
- ✓Telomerase upregulation (preclinical)
- ✓Sleep/circadian normalization
- ✓Anti-aging signals
Key reported benefits — Ipamorelin
- ✓Clean GH release
- ✓Improved sleep quality
- ✓Fat reduction
- ✓Joint health
Educational use only
This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.