What is the difference between CJC-1295 (no DAC) and Hexarelin?

CJC-1295 (no DAC) (Modified Growth Hormone Releasing Factor 1-29) is graded B and is Not FDA-approved — Category 1 (compounding allowed). Hexarelin (Hexarelin (HEX)) is graded B and is Not FDA-approved — research compound (cardioprotective signals investigated). They are commonly compared because they share the categories: growth-hormone, recovery.

Which has stronger clinical evidence — CJC-1295 (no DAC) or Hexarelin?

On our internal evidence scale, CJC-1295 (no DAC) is B and Hexarelin is B. A+ indicates large RCTs plus FDA approval; C indicates primarily preclinical or anecdotal evidence.

What is the typical dose of CJC-1295 (no DAC) vs Hexarelin?

CJC-1295 (no DAC): 100–300 mcg before bed (subcutaneous). Hexarelin: 100 mcg, 1–2 times daily (subcutaneous). Always work with a licensed clinician — peptide dosing should be individualized.

CJC-1295 (no DAC) vs Hexarelin

Both CJC-1295 (no DAC) and Hexarelin are used for growth-hormone and recovery. Here's how their evidence, dosing, and regulatory status actually compare.

CJC-1295 (no DAC)

Evidence B

Modified Growth Hormone Releasing Factor 1-29

A growth hormone releasing hormone (GHRH) analog most commonly stacked with Ipamorelin to stimulate natural GH pulsatile release without disrupting the hypothalamic axis.

View full CJC-1295 (no DAC) profile →

Hexarelin

Evidence B

Hexarelin (HEX)

The strongest GH-releasing hexapeptide and one of the few peptides with documented direct cardiac benefits in animal models. Tachyphylaxis (diminished response over time) limits long-term use.

View full Hexarelin profile →

Side-by-Side

Attribute	CJC-1295 (no DAC)	Hexarelin
Evidence Grade	B	B
FDA Status	Not FDA-approved — Category 1 (compounding allowed)	Not FDA-approved — research compound (cardioprotective signals investigated)
Typical Dose	100–300 mcg before bed (subcutaneous)	100 mcg, 1–2 times daily (subcutaneous)
Clinics Indexed	156	41
Categories	growth-hormone, anti-aging, recovery	growth-hormone, recovery

Key reported benefits — CJC-1295 (no DAC)

✓Growth hormone release
✓Fat loss
✓Improved sleep
✓Muscle recovery

Key reported benefits — Hexarelin

✓Strongest GH spike of GHRPs
✓Cardioprotective signals
✓Recovery

Educational use only

This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.

← Back to all comparisons