BPC-157 vs TB-500
Both BPC-157 and TB-500 are used for recovery. Here's how their evidence, dosing, and regulatory status actually compare.
BPC-157
Evidence B+Body Protection Compound-157
A 15-amino-acid peptide derived from gastric juice. The most popular recovery peptide with 100+ preclinical studies showing accelerated healing of tendons, ligaments, muscle, gut lining, and nerves.
View full BPC-157 profile →TB-500
Evidence BThymosin Beta-4 Fragment
A synthetic fragment of thymosin beta-4 that promotes cell migration, blood vessel formation, and tissue repair. Often stacked with BPC-157 as the 'Wolverine Stack.'
View full TB-500 profile →Side-by-Side
| Attribute | BPC-157 | TB-500 |
|---|---|---|
| Evidence Grade | B+ | B |
| FDA Status | Not FDA-approved — Category 2 (reclassification to Cat 1 expected 2026) | Not FDA-approved — Category 2 (reclassification to Cat 1 expected 2026) |
| Typical Dose | 250–500 mcg twice daily (subcutaneous) | 2 mg twice weekly (subcutaneous) |
| Clinics Indexed | 308 | 183 |
| Categories | recovery, gut-health | recovery, anti-inflammatory |
Key reported benefits — BPC-157
- ✓Tendon & ligament repair
- ✓Gut healing
- ✓Muscle recovery
- ✓Neuroprotection
Key reported benefits — TB-500
- ✓Wound healing
- ✓Anti-inflammation
- ✓Tissue regeneration
- ✓Flexibility
Educational use only
This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.