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AOD-9604 vs Tesamorelin

Both AOD-9604 and Tesamorelin are used for fat-loss. Here's how their evidence, dosing, and regulatory status actually compare.

AOD-9604

Evidence C+

Anti-Obesity Drug 9604

A modified fragment of human growth hormone (hGH 176-191) that stimulates fat breakdown without the growth-promoting or diabetogenic effects of full HGH.

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Tesamorelin

Evidence A

Tesamorelin (Egrifta)

An FDA-approved GHRH analog that stimulates natural growth hormone production. Clinically proven to reduce visceral adipose tissue and increasingly used off-label for body recomposition.

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Side-by-Side

AttributeAOD-9604Tesamorelin
Evidence GradeC+A
FDA StatusNot FDA-approved — Category 1 (compounding allowed)FDA-approved for HIV-associated lipodystrophy
Typical Dose250–500 mcg daily (subcutaneous)2 mg daily (subcutaneous)
Clinics Indexed134178
Categoriesweight-loss, fat-lossgrowth-hormone, fat-loss

Key reported benefits — AOD-9604

  • Fat metabolism
  • No HGH side effects
  • Cartilage repair potential

Key reported benefits — Tesamorelin

  • Visceral fat reduction
  • Natural GH stimulation
  • Cognitive benefit
  • Lean mass

Educational use only

This comparison is for educational purposes and not medical advice. Peptide selection should be made with a licensed medical professional based on your individual goals, health history, and current evidence quality.

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